Opportunity 

Access to sensitive health data remains a major barrier to research, workforce education and digital-health innovation. Synthetic health data can help organisations explore datasets, test analytical pipelines and build capability without directly exposing patient information. But realising this opportunity requires more than technical tools: organisations also need fit-for-purpose governance, validation methods, ethical oversight and public trust.  

Led by La Trobe University with support from the DHCRC Synthetic Data (SynD) Community of Practice and international experts from Swansea University and the Secure Anonymised Information Linkage (SAIL) Databank, this masterclass series aimed to address critical barriers in health data access, privacy, and interoperability by supporting participants to explore federated AI models for multi-site analysis, understand ethical, regulatory, and governance considerations, and get hands-on experience with AI-enhanced low- and high-fidelity synthetic data.  

Project Objectives  

Led by La Trobe University, the project set out to help build Australia’s capability to generate, assess and use synthetic health data responsibly with a targeted education, training, and masterclass series on synthetic health data and AI-driven analytics. The training was designed to equip participants with the skills, knowledge, and confidence to generate, manipulate, and analyse synthetic datasets responsibly and effectively in healthcare research, education, and innovation, connecting technical methods with practical questions about privacy, utility, social licence and organisational adoption.

The two-day masterclasses were delivered in Melbourne, Sydney and Perth in June 2026, reaching 135 participants from research, government, health services, industry and consumer communities.  

The masterclasses combined expert presentations, Australian and international case studies, cross-sector discussion, practical activities and demonstrations. Topics included synthetic-data generation and validation, federated analytics, Trusted Research Environments (TREs), Common Data Models (CDMs) such as OMOP, governance, ethics and social licence. 

Feedback from 51 respondents scored the overall experience 4.5 out of 5, while 84% said they intended to apply their learning. Expert presentations and cross-sector networking received the strongest value ratings. Research and health planning were the leading intended applications, while validation, benchmarking and real-world case studies were the most requested future topics.

The project delivered three masterclasses that strengthened knowledge and confidence in synthetic health data, governance, ethics and privacy-utility decision-making for a cross-section of research, government, health service, industry and consumer representative participants. This workshop approach provides a practical framework for future capability building, governance development and privacy-preserving data linkage in Australian health research using synthetic data. 

It also created a shared forum in which the participants could examine the conditions required for trustworthy generation and adoption of synthetic data, which will support data-driven innovation and emerging technologies such as AI in Australia while maintaining trust, privacy, and social license. 

Integrity, Excellence,
Teamwork and Authenticity

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