CLOTS – technical solution: 4-Model Decision Support Tool for ALL surgical and interventional procedures
Start Date
28 October 2019
End Date
11 September 2025
Project Participants
Status: Completed
Opportunity
Perioperative patients face risks associated with thromboembolism (TE, blood clots in the veins), anticoagulant management and pre-operative optimisation. Despite clinical evidence and established guidelines for best practice care, there is still inconsistent implementation in practice. Clinicians need timely access to appropriate decision-making tools to ensure better patient outcomes.
The project addressed prevention of TE, a high priority safety initiative for the Australian medical community, with a 4-Model Decision Support tool (CLOTS) to drive evidence-based, real time decision-making for surgical procedures.
Project Objectives
This project aimed to enhance and validate a clinical decision support solution that prioritised:
- Surgical TE Prevention (STEP);
- periprocedural management of antithrombotic drugs (MAD);
- haematinic optimisation (HO), to avoid complications associated with anaemia and blood products; and
- fast-track warfarin reversal (FTWR), a novel, highly effective, and safe strategy for warfarin management for elective procedures.
The project sought to provide clinicians with recommendations derived from real-world usage and outcome data, and establish pathways toward commercialisation and wider adoption of this model and tool.


