CLOTS – technical solution: 4-Model Decision Support Tool for ALL surgical and interventional procedures

Start Date

28 October 2019

End Date

11 September 2025

Project Participants

Status: Completed

Opportunity 

Perioperative patients face risks associated with thromboembolism (TE, blood clots in the veins), anticoagulant management and pre-operative optimisation. Despite clinical evidence and established guidelines for best practice care, there is still inconsistent implementation in practice. Clinicians need timely access to appropriate decision-making tools to ensure better patient outcomes.  

The project addressed prevention of TE, a high priority safety initiative for the Australian medical community, with a 4-Model Decision Support tool (CLOTS) to drive evidence-based, real time decision-making for surgical procedures. 

Project Objectives  

This project aimed to enhance and validate a clinical decision support solution that prioritised:  

  • Surgical TE Prevention (STEP);  
  • periprocedural management of antithrombotic drugs (MAD);  
  • haematinic optimisation (HO), to avoid complications associated with anaemia and blood products; and  
  • fast-track warfarin reversal (FTWR), a novel, highly effective, and safe strategy for warfarin management for elective procedures. 

The project sought to provide clinicians with recommendations derived from real-world usage and outcome data, and establish pathways toward commercialisation and wider adoption of this model and tool. 

The project successfully delivered an enhanced CLOTS digital platform consisting of a clinician mobile application, backend data infrastructure, and an analytics dashboard, supported by an assessment of the tool’s commercialisation potential. The project also supported the successful completion of a PhD program. 

CLOTS demonstrates how a digital clinical decision support tool can improve the consistency and accessibility of evidence-based perioperative care. The platform provides a scalable foundation for broader adoption across healthcare settings to support thromboembolism prevention, and generated valuable data for service improvement and future AI-enabled healthcare applications. 

Integrity, Excellence,
Teamwork and Authenticity

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